product summary
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company name :
MyBioSource
product type :
antibody
product name :
MAPT Antibody
catalog :
MBS851873
quantity :
0.1 mg
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS851873 image 1
image 2 :
MyBioSource MBS851873 image 2
product information
catalog number :
MBS851873
products type :
Antibody
products full name :
MAPT Antibody
products short name :
[MAPT]
other names :
[microtubule-associated protein tau isoform 1; Microtubule-associated protein tau; microtubule-associated protein tau; microtubule associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau]
products gene name :
[MAPT]
other gene names :
[MAPT; MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103; MAPTL; MTBT1; TAU; PHF-tau]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
758
form :
Purified by protein A column containing 0.02% NaN3
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 1:10,000-1:80,000. WB: 1:200-1:1,000
image1 heading :
Testing Data
image2 heading :
Testing Data
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products description :
Rabbit polyclonal MAPT (1) antibody was raised against a recombinate human MAPT protein 642-754aa(NM_016835).
products references :
(1) Skoglund, L., Ingvast, S., Matsui, T., et al. No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration.Dement Geriatr Cogn Disord 28 (5), 471-475 (2009).
ncbi gi num :
294862261
ncbi acc num :
NP_058519.3
ncbi gb acc num :
NM_016835.4
uniprot acc num :
P10636
ncbi mol weight :
80,941 Da
ncbi pathways :
Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Apoptosis Pathway (105648); Apoptotic Cleavage Of Cellular Proteins Pathway (105678); Apoptotic Execution Phase Pathway (105677); BDNF Signaling Pathway (712093); Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway (105679); IL-2 Signaling Pathway (198885); IL-6 Signaling Pathway (198864)
ncbi summary :
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
uniprot summary :
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
size1 :
0.1 mg
price1 :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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