product summary
Loading...
company name :
MyBioSource
product type :
other
product name :
CHRNB4 Antibody
catalog :
MBS8518708
quantity :
0.1 mg
price :
290 USD
more info or order :
image
image 1 :
MyBioSource MBS8518708 image 1
Western blot analysis CHRNB4 using HuvEc whole cell lysates
product information
catalog number :
MBS8518708
products type :
Antibody
products full name :
CHRNB4 Antibody
products short name :
[CHRNB4]
other names :
[neuronal acetylcholine receptor subunit beta-4 isoform 1; Neuronal acetylcholine receptor subunit beta-4; neuronal acetylcholine receptor subunit beta-4; cholinergic receptor nicotinic beta 4 subunit]
products gene name :
[CHRNB4]
other gene names :
[CHRNB4; CHRNB4]
sequence length :
498
image1 heading :
Western Blot (WB)
ncbi gi num :
4502837
ncbi acc num :
NP_000741.1
ncbi gb acc num :
NM_000750.4
uniprot acc num :
P30926
ncbi mol weight :
25,862 Da
ncbi pathways :
Acetylcholine Binding And Downstream Events Pathway (106535); Activation Of Nicotinic Acetylcholine Receptors Pathway (161027); Cholinergic Synapse Pathway (217716); Highly Calcium Permeable Nicotinic Acetylcholine Receptors Pathway (161029); Highly Calcium Permeable Postsynaptic Nicotinic Acetylcholine Receptors Pathway (161032); Highly Sodium Permeable Acetylcholine Nicotinic Receptors Pathway (161030); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Neuronal System Pathway (106513); Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway (106534)
ncbi summary :
This gene is found within a conserved gene cluster and encodes one of the beta subunits of the nicotinic acetylcholine receptor (nAChRs) superfamily which form ligand-gated ion channels with a central pore that forms a cation channel. Neuronal nAChRs are pentameric structures that can be either homomeric or heteromeric, with heteromeric structures containing both alpha and beta subunits. Each subunit contains an extracellular amino terminus and four transmembrane domains. Nicotine is one of the agonists that binds to the receptor. Variants in this gene have been associated with nicotine dependence and lung cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2017]
uniprot summary :
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!