catalog number :
MBS851811
products full name :
TGF beta 1 Antibody
products short name :
TGF beta 1
products name syn :
TGFb1 Antibody
other names :
transforming growth factor beta-1; Transforming growth factor beta-1; transforming growth factor beta-1; TGF-beta-1; latency-associated peptide; prepro-transforming growth factor beta-1; transforming growth factor, beta 1
other gene names :
TGFB1; TGFB1; CED; LAP; DPD1; TGFB; TGFbeta; TGFB; TGF-beta-1; LAP
uniprot entry name :
TGFB1_HUMAN
specificity :
Anti-TGFbeta1 recognizes recombinant protein TGFbeta1.
form :
Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
storage stability :
The antibody may be stored at -20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
tested application :
ELISA (EIA), Western Blot (WB-Re)
other info1 :
Source Note: Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein TGFbeta1 as immunogen.
other info2 :
Immunogen: Recombinant protein corresponding to fragment (aa/1-111) TGFbeta1.
products categories :
Plant antibody
ncbi acc num :
NP_000651.3
ncbi gb acc num :
NM_000660.3
ncbi mol weight :
44,341 Da
ncbi pathways :
ACE Inhibitor Pathway 198763!!ALK1 Signaling Events Pathway 137968!!Adipogenesis Pathway 198832!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Cardiac Progenitor Differentiation Pathway 712094!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463!!Chagas Disease (American Trypanosomiasis) Pathway 147809
ncbi summary :
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]