product summary
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company name :
MyBioSource
product type :
antibody
product name :
PPP1R2 (Ab-120/121) Antibody
catalog :
MBS851753
quantity :
0.1 mg
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS851753
products type :
Antibody
products full name :
PPP1R2 (Ab-120/121) Antibody
products short name :
PPP1R2
products name syn :
I-2; IPP-2; IPP2; Protein phosphatase inhibitor 2
other names :
protein phosphatase inhibitor 2 isoform 2; Protein phosphatase inhibitor 2; protein phosphatase inhibitor 2; phosphoprotein phosphatase; protein phosphatase 1, regulatory (inhibitor) subunit 2
products gene name :
PPP1R2
other gene names :
PPP1R2; PPP1R2; IPP2; IPP-2; IPP2; IPP-2
uniprot entry name :
IPP2_HUMAN
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
205
specificity :
PPP1R2 (Ab-120/121) antibody detects endogenous levels of total PPP1R2 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:5000
other info2 :
Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human PPP1R2 around the phosphorylation site of serine 120 and serine 121 (Q-E-SP-SP-G-E). Pathway: Intermediates
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Sanseau P., Mamm. Genome 5:490-496(1994). Helps N.R., FEBS Lett. 340:93-98(1994). Permana P.A., Genomics 41:110-114(1997).
ncbi gi num :
5453946
ncbi acc num :
NP_006232.1
ncbi gb acc num :
NM_006241.7
uniprot acc num :
P41236
ncbi mol weight :
23,015 Da
uniprot summary :
PPP1R2: a member of the protein phosphatase inhibitor 1 family. A dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Both dopaminergic and glutamatergic (NMDA) receptor stimulation regulate the extent of DARPP32 phosphorylation, but in opposite directions. Dopamine D1 receptor stimulation enhances cAMP formation, resulting in the phosphorylation of DARPP32; phosphorylated DARPP32 is a potent protein phosphatase-1 inhibitor. NMDA receptor stimulation elevates intracellular calcium, which leads to activation of calcineurin and dephosphorylation of phospho-DARPP32, thereby reducing the phosphatase-1 inhibitory activity of DARPP32. Two alternatively-spliced isoforms have been described. Protein type: Motility/polarity/chemotaxis; Inhibitor; Protein phosphatase, regulatory subunit. Chromosomal Location of Human Ortholog: 3q29. Molecular Function: protein binding; type 1 serine/threonine specific protein phosphatase inhibitor activity. Biological Process: glycogen metabolic process; generation of precursor metabolites and energy; negative regulation of catalytic activity; regulation of signal transduction; regulation of phosphoprotein phosphatase activity
size1 :
0.1 mg
price1 :
215 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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