EREG Antibody | MyBioSource MBS851725 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

EREG Antibody

catalog :

MBS851725

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS851725

products type :

Antibody

products full name :

EREG Antibody

products short name :

EREG

other names :

Homo sapiens epiregulin (EREG), mRNA; Proepiregulin; proepiregulin; epiregulin

products gene name :

EREG

other gene names :

EREG; EREG; ER; EPR

uniprot entry name :

EREG_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human

sequence length :

4628

form :

Lyophilized anti-EREG antibody purified by peptide affinity column containing 0.5% BSA and 0.02% NaN3

concentration :

100ug/200ul

storage stability :

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: 1:1,000-1:10,000. Western blot: 1:200-1:1000. Immunohistochemistry: 1:50-1:200. Not tested in other applications.

other info1 :

Source Note: Rabbit polyclonal EREG (1) antibody was raised against a 13 amino acid peptide from the intermediate residues of human EREG protein. Reactivity Note: Not yet tested in other species.

other info2 :

Pathway: epiregulin

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

ncbi gi num :

119703747

ncbi acc num :

NP_001423.1

ncbi gb acc num :

NM_001432

ncbi mol weight :

19,044 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR Pathway (160957); ErbB Receptor Signaling Network Pathway (138016); ErbB Signaling Pathway (198844)

ncbi summary :

Epiregulin is a member of the epidermal growth factor family. Epiregulin can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. [provided by RefSeq, Jul 2008]

uniprot summary :

Epiregulin: Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; integral to plasma membrane; extracellular region. Molecular Function: protein binding; growth factor activity; epidermal growth factor receptor binding. Biological Process: response to peptide hormone stimulus; nerve growth factor receptor signaling pathway; wound healing; activation of MAPK activity; positive regulation of smooth muscle cell proliferation; positive regulation of interleukin-6 biosynthetic process; female meiosis; negative regulation of smooth muscle cell differentiation; negative regulation of cell proliferation; positive regulation of fibroblast proliferation; primary follicle stage, oogenesis; positive regulation of epidermal growth factor receptor activity; cell-cell signaling; positive regulation of cell proliferation; positive regulation of innate immune response; ovarian cumulus expansion; angiogenesis; negative regulation of epithelial cell proliferation; positive regulation of cytokine production; epidermal growth factor receptor signaling pathway; anatomical structure morphogenesis; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; positive regulation of mitosis; cytokine and chemokine mediated signaling pathway; positive regulation of cytokine biosynthetic process; keratinocyte proliferation; luteinizing hormone signaling pathway; oocyte maturation; ovulation; keratinocyte differentiation; organ morphogenesis; positive regulation of protein kinase activity; mRNA transcription; innate immune response; negative regulation of transcription, DNA-dependent; positive regulation of DNA replication; positive regulation of phosphorylation

size1 :

0.1 mg

price1 :

290 USD

more info or order :

MyBioSource product webpage