product summary
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company name :
MyBioSource
product type :
antibody
product name :
TNKS2 Antibody
catalog :
MBS851677
quantity :
0.1 mg
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS851677 image 1
image 2 :
MyBioSource MBS851677 image 2
product information
catalog number :
MBS851677
products type :
Antibody
products full name :
TNKS2 Antibody
products short name :
[TNKS2]
other names :
[tankyrase-2; Tankyrase-2; tankyrase-2; tankyrase 2; ADP-ribosyltransferase diphtheria toxin-like 6; ARTD6; Poly [ADP-ribose] polymerase 5B; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2; Tankyrase II; Tankyrase-like protein; Tankyrase-related protein]
products gene name :
[TNKS2]
other gene names :
[TNKS2; TNKS2; TNKL; ARTD6; TANK2; pART6; PARP5B; PARP5C; PARP-5b; PARP-5c; PARP5B; TANK2; TNKL; TANK2; ARTD6]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Rat, Mouse
sequence length :
1166
form :
Lyophilized anti-TNKS2 anitbody purified by peptide affinity column containing 1% BSA and 0.02% NaN 3
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: 1:10,000-1:40,000. WB: 1:1,000-1:2,000. IHC: 1:100-1:500
image1 heading :
Testing Data
image2 heading :
Testing Data
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products description :
Rabbit polyclonal TNKS2 (1) antibody was raised against a peptide from C terminal residues of human TNKS2 protein.
products references :
(1) Casabonne, D., Reina, O., Benavente, Y., et al. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. Haematologica 96 (2), 323-327 (2011).
ncbi gi num :
13376842
ncbi acc num :
NP_079511.1
ncbi gb acc num :
NM_025235.3
uniprot acc num :
Q9H2K2
ncbi mol weight :
126,918 Da
ncbi pathways :
Disease Pathway (530764); RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway (1127632); Signal Transduction Pathway (477114); Signaling By WNT In Cancer Pathway (1127614); Signaling By Wnt Pathway (106510); TCF Dependent Signaling In Response To WNT Pathway (1127516); XAV939 Inhibits Tankyrase, Stabilizing AXIN Pathway (1127633); Degradation Of AXIN Pathway (1127523); Misspliced LRP5 Mutants Have Enhanced Beta-catenin-dependent Signaling Pathway (1127631)
uniprot summary :
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Stimulates 26S proteasome activity.
size1 :
0.1 mg
price1 :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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