SSTR1 Antibody | MyBioSource MBS851536 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

SSTR1 Antibody

catalog :

MBS851536

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS851536

products type :

Antibody

products full name :

SSTR1 Antibody

products short name :

SSTR1

products name syn :

Somatostatin receptor type 1; SS1R; SRIF-2

other names :

somatostatin receptor type 1; Somatostatin receptor type 1; somatostatin receptor type 1; somatostatin receptor 1; SRIF-2

products gene name :

SSTR1

other gene names :

SSTR1; SSTR1; SS1R; SS1-R; SRIF-2; SS-1-R; SS-1-R; SS1-R; SS1R

uniprot entry name :

SSR1_HUMAN

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

391

specificity :

SSTR1 antibody detects endogenous levels of total SSTR1 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)

app notes :

WB: 1:500~1:1000, IF: 1:100~1:500, ELISA: 1:20000

other info2 :

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human SSTR1. Pathway: GPCR

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Yamada Y., Proc. Natl. Acad. Sci. U.S.A. 89:251-255(1992). The MGC Project Team; Genome Res. 14:2121-2127(2004). Schwaerzler A., J. Biol. Chem. 275:9557-9562(2000).

ncbi gi num :

4557857

ncbi acc num :

NP_001040.1

ncbi gb acc num :

NM_001049.2

uniprot acc num :

P30872

ncbi mol weight :

42,686 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Peptide GPCRs Pathway (198897); Peptide Ligand-binding Receptors Pathway (106358); SIDS Susceptibility Pathways (198901)

ncbi summary :

Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012]

uniprot summary :

SSTR1: Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. Belongs to the G-protein coupled receptor 1 family. Interacts with SKB1. Protein type: Membrane protein, multi-pass; Receptor, GPCR; Cell cycle regulation; GPCR, family 1; Membrane protein, integral. Chromosomal Location of Human Ortholog: 14q13. Cellular Component: neuron projection; integral to plasma membrane; cytoplasm; plasma membrane. Molecular Function: neuropeptide binding; somatostatin receptor activity. Biological Process: glutamate signaling pathway; response to starvation; negative regulation of cell proliferation; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; cell surface receptor linked signal transduction; cell-cell signaling; neuropeptide signaling pathway; forebrain development; digestion; cerebellum development; spermatogenesis; response to nutrient

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage