product summary
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company name :
MyBioSource
product type :
other
product name :
TFEB Antibody
catalog :
MBS8513851
quantity :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8513851 image 1
Western blot analysis of extracts from mouse lung cells and mouse muscle cells, using TFEB antibody
product information
catalog number :
MBS8513851
products type :
Antibody
products full name :
TFEB Antibody
products short name :
[TFEB]
products name syn :
[Transcription factor EB; TFEB]
other names :
[transcription factor EB isoform 2; Transcription factor EB; transcription factor EB; transcription factor EB; Class E basic helix-loop-helix protein 35; bHLHe35]
products gene name :
[TFEB]
other gene names :
[TFEB; TFEB; TCFEB; BHLHE35; ALPHATFEB; BHLHE35; bHLHe35]
reactivity :
Human, Mouse
sequence length :
490
specificity :
TFEB Antibody detects endogenous levels of total TFEB
purity :
Immunogen affinity purified
form :
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:1000. IHC: 1:50-1:200
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide
ncbi gi num :
429836865
ncbi acc num :
NP_001161299.2
ncbi gb acc num :
NM_001167827.2
uniprot acc num :
P19484
ncbi mol weight :
52 KD
uniprot summary :
Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
size1 :
0.1 mg
price1 :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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