catalog number :
MBS8513555
products full name :
TAS1R1 Antibody
products short name :
[TAS1R1]
other names :
[taste receptor type 1 member 1 isoform b; Taste receptor type 1 member 1; taste receptor type 1 member 1; taste 1 receptor member 1; G-protein coupled receptor 70]
products gene name :
[TAS1R1]
other gene names :
[TAS1R1; TAS1R1; TR1; T1R1; GM148; GPR70; GPR70; T1R1; TR1]
image1 heading :
Western Blot (WB)
ncbi acc num :
NP_619642.2
ncbi gb acc num :
NM_138697.3
ncbi mol weight :
35,134 Da
ncbi pathways :
Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway (106381); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); GPCR Ligand Binding Pathway (161020); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); Taste Transduction Pathway (83088); Taste Transduction Pathway (499)
ncbi summary :
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
uniprot summary :
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.