catalog number :
MBS851336
products full name :
PRDX6 Antibody
products short name :
[PRDX6]
other names :
[peroxiredoxin-6; Peroxiredoxin-6; peroxiredoxin-6; peroxiredoxin 6; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2 (EC:3.1.1.4]
products gene name :
[PRDX6]
other gene names :
[PRDX6; PRDX6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m; AOP2; KIAA0106; aiPLA2; NSGPx]
specificity :
Anti-PRDX6 recognizes recombinant protein PRDX6.
form :
Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
storage stability :
The antibody may be stored at-20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
tested application :
ELISA (EIA), Western Blot (WB-Ce)
image1 heading :
Western Blot
other info1 :
Immunogen: Recombinant protein corresponding to full length PRDX6.
products categories :
Plant antibody
products description :
Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein PRDX6 as immunogen.
ncbi acc num :
NP_004896.1
ncbi gb acc num :
NM_004905.2
ncbi mol weight :
25,035 Da
ncbi pathways :
Cellular Responses To Stress Pathway (645258); Detoxification Of Reactive Oxygen Species Pathway (1127552); Metabolic Pathways (132956); Phenylalanine Metabolism Pathway (82960); Phenylalanine Metabolism Pathway (327)
ncbi summary :
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
uniprot summary :
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.