product summary
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company name :
MyBioSource
product type :
other
product name :
GRM5 Antibody
catalog :
MBS8511874
quantity :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8511874 image 1
Western blot analysis of GRM5 expression in HT-29 cells
product information
catalog number :
MBS8511874
products type :
Antibody
products full name :
GRM5 Antibody
products short name :
[GRM5]
products name syn :
[GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5]
other names :
[metabotropic glutamate receptor 5 isoform b; Metabotropic glutamate receptor 5; metabotropic glutamate receptor 5; glutamate metabotropic receptor 5]
products gene name :
[GRM5]
other gene names :
[GRM5; GRM5; mGlu5; GPRC1E; MGLUR5; PPP1R86; GPRC1E; MGLUR5; mGluR5]
reactivity :
Human, Mouse, Rat
sequence length :
1180
specificity :
GRM5 antibody detects endogenous levels of total GRM5 protein.
purity :
Immunogen affinity purified
form :
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year
tested application :
Western Blot (WB), Immunofluorescence (IF)
app notes :
WB: 1:500-1:1000. IF: 1:200
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from internal of human GRM5.
products description :
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current
ncbi gi num :
4504143
ncbi acc num :
NP_000833.1
ncbi gb acc num :
NM_000842.4
uniprot acc num :
P41594
ncbi mol weight :
120kd
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway (106381); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class C Metabotropic Glutamate, Pheromone Pathway (198839); Gap Junction Pathway (83072)
ncbi summary :
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
uniprot summary :
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
size1 :
0.1 mg
price1 :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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