antibody

annexin A5 Antibody

MBS851093

0.1 mg

290 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry

Antibody

annexin A5 Antibody

annexin A5

Homo sapiens annexin A5 (ANXA5), mRNA; Annexin A5; annexin A5; CBP-I; PAP-I; VAC-alpha; annexin V; annexin-5; anchorin CII; endonexin II; lipocortin V; calphobindin I; thromboplastin inhibitor; vascular anticoagulant-alpha; epididymis secretory protein Li 7; placental anticoagulant protein 4; placental anticoagulant protein I; annexin A5; Anchorin CII; Annexin V; Annexin-5; Calphobindin I; CBP-I; Endonexin II; Lipocortin V; Placental anticoagulant protein 4; PP4; Placental anticoagulant protein I; PAP-I; Thromboplastin inhibitor; Vascular anticoagulant-alpha; VAC-alpha

ANXA5; ANXA5; PP4; ANX5; ENX2; RPRGL3; HEL-S-7; ANX5; ENX2; PP4; CBP-I; PP4; PAP-I; VAC-alpha

ANXA5_HUMAN

Polyclonal

Rabbit

Human, Mouse, Rat

1624

Lyophilized annexin A5 antibody purified by protein A column containing 0.02% NaN3

100ug/200ul

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Western Blot (WB), Immunohistochemistry (IHC)

ELISA titer: 1:10,000-1:80,000. Western blot analysis: 1:200-1:1,000. Immunohistochemistry: 1:50-200. Optimal dilutions/concentrations should be determined by the end user.

Source Note: Rabbit polyclonal annexin A5 (1) antibody was raised against a recombinate human annexin A5 protein 146-255aa (NM_001154). Reactivity Note: Not yet tested in other species.

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

186680508

NP_001145.1

NM_001154

35,937 Da

Prostaglandin Synthesis And Regulation Pathway (198912)

The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq, Jul 2008]

ANXA5: a calcium/phospholipid-binding protein and an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. The binding of labeled ANXA5 to phosphatidylserine is used as a marker of apoptosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion. Protein type: Apoptosis; Inhibitor; Calcium-binding; Lipid-binding. Chromosomal Location of Human Ortholog: 4q27. Cellular Component: focal adhesion; membrane; cytoplasm; intracellular; external side of plasma membrane. Molecular Function: phospholipase inhibitor activity; calcium-dependent phospholipid binding; phospholipid binding; calcium ion binding. Biological Process: response to organic substance; negative regulation of catalytic activity; negative regulation of coagulation; signal transduction; blood coagulation; negative regulation of apoptosis. Disease: Pregnancy Loss, Recurrent, Susceptibility To, 3

0.1 mg

290 USD