product summary
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company name :
MyBioSource
product type :
other
product name :
Keratin 8 Antibody
catalog :
MBS8510691
quantity :
0.1 mg
price :
290 USD
more info or order :
image
image 1 :
Western Blot analysis of various cells using Keratin 8 Antibody ?MBS8510691? diluted at 1?2000.
image 2 :
Keratin 8 Antibody ?MBS8510691?diluted at 1:100 staining human kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
product information
catalog number :
MBS8510691
products type :
Antibody
products full name :
Keratin 8 Antibody
products short name :
[Keratin 8]
products name syn :
[CARD2; CK-8; CK8; CYK8; cytokeratin 8; Cytokeratin-8; K2C8; K8; keratin 8; Keratin, type II cytoskeletal 8; Keratin-8; KO; Type-II keratin Kb8]
other names :
[keratin, type II cytoskeletal 8 isoform 2; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8; keratin 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8]
products gene name :
[KRT8]
other gene names :
[KRT8; KRT8; K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; CYK8; CK-8; K8]
reactivity :
Human, Mouse, Rat
sequence length :
483
specificity :
Keratin 8 antibody detects endogenous levels of total Keratin 8
purity :
Affinity-chromatography
form :
Rabbit IgG phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20°C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500~1:3000. IHC: 1:50~1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: A synthesized peptide derived from human Keratin 8
products description :
K8 a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Phsophorylated by p38 kinase, regulating cellular keratin filament reorganization.
ncbi gi num :
372466577
ncbi acc num :
NP_001243222.1
ncbi gb acc num :
NM_001256293.1
uniprot acc num :
P05787
ncbi mol weight :
55 kDa
ncbi pathways :
EGFR1 Signaling Pathway (198782); Signaling Mediated By P38-alpha And P38-beta Pathway (138012)
ncbi summary :
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
uniprot summary :
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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