catalog number :
MBS850954
products full name :
TEC Antibody
products short name :
TEC
products name syn :
PSCTK4
other names :
tyrosine-protein kinase Tec; Tyrosine-protein kinase Tec; tyrosine-protein kinase Tec; tec protein tyrosine kinase
other gene names :
TEC; TEC; PSCTK4; PSCTK4
uniprot entry name :
TEC_HUMAN
form :
Ascitic fluid containing 0.03% sodium azide.
concentration :
100ug/100ul
storage stability :
Store at 4 degree C. For long term storage, store at -20 degree C
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
other info2 :
Immunogen: Purified recombinant fragment of TEC expressed in E. Coli. Species: Mouse IgG1
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
ncbi acc num :
NP_003206.2
ncbi gb acc num :
NM_003215.2
ncbi pathways :
B Cell Receptor Signaling Pathway 198909!!Cytokine Signaling In Immune System Pathway 366171!!EPO Signaling Pathway 138051!!FCERI Mediated Ca+2 Mobilization Pathway 833827!!Fc Epsilon Receptor (FCERI) Signaling Pathway 833825!!IL-3 Signaling Pathway 198881!!IL-6 Signaling Pathway 198864!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Interleukin-3, 5 And GM-CSF Signaling Pathway 187094
ncbi summary :
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]