product summary
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company name :
MyBioSource
product type :
antibody
product name :
NGLY1 Antibody (Rabbit Polyclonal)
catalog :
MBS8509075
quantity :
0.1 mg
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8509075 image 1
image 2 :
MyBioSource MBS8509075 image 2
product information
catalog number :
MBS8509075
products type :
Antibody
products full name :
NGLY1 Antibody (Rabbit Polyclonal)
products short name :
[NGLY1]
other names :
[Homo sapiens N-glycanase 1, mRNA; Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; N-glycanase 1; N-glycanase 1; Peptide:N-glycanase]
products gene name :
[NGLY1]
other gene names :
[NGLY1; NGLY1; CDDG; PNG1; CDG1V; PNGase; PNG1; PNGase; hPNGase]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human. Predicted: Rat, Mouse
sequence length :
2213
form :
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA: 1:20,000-1:80,000. WB: 1:200-1:1,000. IHC: 1:100-1:500
image1 heading :
Immunohistochemistry
image2 heading :
Western Blot
products description :
Rabbit polyclonal NGLY1 (1) antibody was raised against a recombinate human NGLY1 protein 327-538aa (BC007226). Species Reactivity:
ncbi gi num :
13938210
ncbi acc num :
BC007226
ncbi mol weight :
70,211 Da
ncbi pathways :
Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190)
ncbi summary :
This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009]
uniprot summary :
Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.
size1 :
0.1 mg
price1 :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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