antibody

FMR1 Antibody

MBS850895

0.1 mg

290 USD

monoclonal

mouse

nonconjugated

4G9

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

FMR1 Antibody

FMR1

POF; FMRP; POF1; FRAXA

fragile X mental retardation protein 1 isoform ISO6; Fragile X mental retardation protein 1; fragile X mental retardation protein 1; fragile X mental retardation 1

FMR1

FMR1; FMR1; POF; FMRP; POF1; FRAXA; FMRP; Protein FMR-1

FMR1_HUMAN

Monoclonal

4G9

Mouse

Human

537

Ascitic fluid containing 0.03% sodium azide.

100ug/100ul

Store at 4 degree C. For long term storage, store at -20 degree C

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.

Immunogen: Purified recombinant fragment of human FMR1 expressed in E. Coli. Species: Mouse IgG1

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Background: FMR1, also known as POF, FMRP, FRAXA. Entrez Protein. NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5 UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.

297374777

NP_001172004.1

NM_001185075.1

71kDa

RNA Transport Pathway 177876!!RNA Transport Pathway 175229

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

0.1 mg

290 USD