catalog number :
MBS8508514
products full name :
BTNL2 Antibody (Rabbit Polyclonal)
products short name :
[BTNL2]
other names :
[Homo sapiens butyrophilin-like 2 (MHC class II associated), mRNA; Butyrophilin-like protein 2; butyrophilin-like protein 2; butyrophilin like 2]
products gene name :
[BTNL2]
other gene names :
[BTNL2; BTNL2; SS2; BTN7; BTL-II; HSBLMHC1; BTL-II]
reactivity :
Human. Predicted: Rat, Mouse. Not yet tested in other species.
form :
Antibody purified by protein affinity column containing 1% BSA and 0.02% NaN3
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA: 1:20,000-1:80,000. WB: 1:200-1:1,000. IHC: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.
image1 heading :
Western Blot
image2 heading :
Immunohistochemistry
other info1 :
Source Note: Rabbit polyclonal BTNL2(1) antibody was raised against a recombinate human BTNL2 protein 54-245aa (BC127642).
products description :
Rabbit polyclonal BTNL2(1) antibody was raised against a recombinate human BTNL2 protein 54-245aa (BC127642).
ncbi mol weight :
28,660 Da
ncbi summary :
This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. [provided by RefSeq, May 2017]
uniprot summary :
Negative regulator of T-cell proliferation.