other

CHD3 Antibody

MBS850835

0.05 mg

215 USD

Antibody

CHD3 Antibody

[CHD3]

[Mouse monoclonal IgG to CHD3]

[chromodomain-helicase-DNA-binding protein 3 isoform 3; Chromodomain-helicase-DNA-binding protein 3; chromodomain-helicase-DNA-binding protein 3; chromodomain helicase DNA binding protein 3; ATP-dependent helicase CHD3; Mi-2 autoantigen 240 kDa protein; Mi2-alpha; Zinc finger helicase; hZFH]

[CHD3]

[CHD3; CHD3; ZFH; Mi-2a; Mi2-ALPHA; CHD-3; hZFH]

Human

2059

Protein G-Sepharose affinity purified.

Liquid

Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.

ELISA (EIA), Western Blot (WB)

ELISA: 1:5000-1:20000. WB: 1:100-1:2000

Testing Data

Immunogen: Recombinant fragment of Human CHD3 (C-terminus). Preservative: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4. Cellular Localization: Nucleus

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription.

158420731

NP_001005271.2

NM_001005271

Q12873

233,037 Da

Signaling Events Mediated By HDAC Class I Pathway (137997)

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.

0.05 mg

215 USD

0.1 mg

280