product summary
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company name :
MyBioSource
product type :
antibody
product name :
CHD3 Antibody
catalog :
MBS850786
quantity :
0.1 mg
price :
280 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[2G4]
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, FACS, enzyme immunoassay
more info or order :
image
image 1 :
Figure 1: Western blot analysis using CHD3 mouse mAb against Hela (1), K562 (2), Jurkat (3), NTERA-2 (4), HEK293 (5), Raji (6) cell lysate and mouse brain (7) tissue lysate.
image 2 :
Figure 2: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using CHD3 mouse mAb with DAB staining.
image 3 :
Figure 3: Immunofluorescence analysis of Hela cells using CHD3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
product information
catalog number :
MBS850786
products type :
Antibody
products full name :
CHD3 Antibody
products short name :
[CHD3]
products name syn :
[ZFH; Mi-2a; Mi2-ALPHA; CHD3]
other names :
[chromodomain-helicase-DNA-binding protein 3 isoform 3; Chromodomain-helicase-DNA-binding protein 3; chromodomain-helicase-DNA-binding protein 3; chromodomain helicase DNA binding protein 3; ATP-dependent helicase CHD3; Mi-2 autoantigen 240 kDa protein; Mi2-alpha; Zinc finger helicase; hZFH]
products gene name :
[CHD3]
other gene names :
[CHD3; CHD3; ZFH; Mi-2a; Mi2-ALPHA; CHD-3; hZFH]
clonality :
m
isotype :
IgG1
clone :
[2G4]
host :
Mouse
reactivity :
Human, Mouse
sequence length :
2059
form :
Ascitic fluid containing 0.03% sodium azide.
storage stability :
Store at 4 degree C, for long term storage, store at-20 degree C
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA)
app notes :
WB: 1:500-1:2000. IHC: 1:200-1:1000. IF: 1:200-1:1000. FC: 1:200-1:400. ELISA: 1:10000
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli.
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products description :
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
ncbi gi num :
158420731
ncbi acc num :
NP_001005271.2
ncbi gb acc num :
NM_001005271.2
uniprot acc num :
Q12873
ncbi mol weight :
226kDa
ncbi pathways :
Signaling Events Mediated By HDAC Class I Pathway (137997)
ncbi summary :
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
uniprot summary :
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.
size1 :
0.1 mg
price1 :
280 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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