product summary
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company name :
MyBioSource
product type :
other
product name :
NMDAR1 Antibody
catalog :
MBS8507033
quantity :
0.1 mg
price :
215 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8507033 image 1
Western blot analysis of NMDAR1 expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide
product information
catalog number :
MBS8507033
products type :
Antibody
products full name :
NMDAR1 Antibody
products short name :
[NMDAR1]
products name syn :
[GLURZ1; GRIN1; Glutamate [NMDA] receptor subunit zeta 1 precursor; N-methyl-D-aspartate receptor; NMD-R1; NMDZ1; NMZ1; NR1]
other names :
[glutamate receptor ionotropic, NMDA 1 isoform GluN1-4a; Glutamate receptor ionotropic, NMDA 1; glutamate receptor ionotropic, NMDA 1; glutamate ionotropic receptor NMDA type subunit 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1]
products gene name :
[NMDAR1]
other gene names :
[GRIN1; GRIN1; NR1; MRD8; GluN1; NMDA1; NDHMSD; NDHMSR; NMD-R1; NMDAR1; NMDAR1; GluN1; NMD-R1]
reactivity :
Human, Mouse, Rat
sequence length :
885
specificity :
NMDAR1 Antibody detects endogenous levels of total NMDAR1
purity :
Immunogen affinity purified
form :
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000. IHC: 1:50-1:200
image1 heading :
Western Blot
other info1 :
Immunogen: A synthesized peptide derived from human NMDAR1
products description :
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. The gene consists of 21 exons and is alternatively spliced, producing transcript variants differing in the C-terminus.
ncbi gi num :
11496971
ncbi acc num :
NP_000823.4
ncbi gb acc num :
NM_000832.6
uniprot acc num :
Q05586
ncbi mol weight :
120kDa
ncbi pathways :
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (161033); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511)
ncbi summary :
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
uniprot summary :
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761).
size1 :
0.1 mg
price1 :
215 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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