product summary
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company name :
MyBioSource
product type :
other
product name :
TAK-875
catalog :
MBS8506575
quantity :
5 mg
price :
845 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS8506575
products type :
Inhibitor
products full name :
TAK-875
products short name :
[TAK-875]
products gene name :
[TAK-875]
storage stability :
Stable for; 2 years at -20 degree C Powder. 1 week -4 degree C in DMSO. 1 month -80 degree C in DMSO
image1 heading :
Testing Data
other info1 :
Solubility: DMSO >=105 mg/mL - Water =11 mg/mL
other info2 :
Formula: C29H32O7S.1/2H2O. CAS Number: 1000413-72-8
products categories :
Stem Cells; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction
products description :
TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with an EC50 of 0.072 muM. TAK-875 is a new agent applied in the treatment of type 2 diabetes. TAK-875 not only elevated the levels of intra-cellular inositol monophosphate as well as calcium contents in rat insulinoma INS-1 833/15 cells but also improved the tolerance of glucose and amplified insulin secretion when orally administered in tolerance test. However, TAK-875 didn't increase the secretion of insulin and cause hypoglycemia when 30 mg/kg dosage of TAK-875 was given in fasted normal Sprague Dawley rats. Conversely, TAK-875 with a dosage of 10 mg/kg (p.o.) not only significantly improved plasma insulin levels but also decreased fasting hyperglycemia in male Zucker diabetic fatty rats. [1][2]
ncbi mol weight :
533.63
size1 :
5 mg
price1 :
845 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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