product summary
Loading...
company name :
MyBioSource
product type :
other
product name :
PD0325901
catalog :
MBS8506358
quantity :
5 mg
price :
220 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS8506358
products type :
Inhibitor
products full name :
PD0325901
products short name :
[PD0325901]
products gene name :
[PD0325901]
purity :
0.98
storage stability :
Store at-20 degree C 2 years.
image1 heading :
Testing Data
other info1 :
Solubility: DMSO >=96mg/mL - Water =96mg/mL
other info2 :
Formula: C16H14F3IN2O4. CAS Number: 391210-10-9
products categories :
Stem Cells; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction
products description :
PD0325901 is non-competitive with ATP and is exquisitely specific and highly potent against purified MEK, exhibiting a Kiapp of 1 nM against activated MEK1 and MEK2. PD0325901 is roughly 500-fold more potent than CI-1040 with respect to its cellular effects on phosphorylation of ERK1 and ERK2, exhibiting subnanomolar activity. A single oral dose of PD0325901 (25 mg/kg) suppressed phosphorylation of ERK by >50% at 24 hours post-dosing. Anticancer activity of PD 0325901 has been demonstrated for a broad spectrum of human tumor xenografts, significantly inhibiting the growth of 6 out of 7 human tumor models tested. [1]
ncbi mol weight :
482.19
size1 :
5 mg
price1 :
220 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!