catalog number :
MBS850615
products full name :
PSIP1 Antibody
products short name :
PSIP1
products name syn :
p52; p75; PAIP; DFS70; LEDGF; PSIP2; MGC74712; PSIP1
other names :
PC4 and SFRS1-interacting protein isoform 2; PC4 and SFRS1-interacting protein; PC4 and SFRS1-interacting protein; DFS 70; CLL-associated antigen KW-7; dense fine speckles 70 kDa protein; transcriptional coactivator p52/p75; transcriptional coactivator p75/p52; lens epithelium-derived growth factor; PC4 and SFRS1 interacting protein 1; CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; Transcriptional coactivator p75/p52
products gene name :
PSIP1
other gene names :
PSIP1; PSIP1; p52; p75; PAIP; DFS70; LEDGF; PSIP2; DFS70; LEDGF; PSIP2; DFS 70
uniprot entry name :
PSIP1_HUMAN
reactivity :
Human, Monkey, Rat
form :
Ascitic fluid containing 0.03% sodium azide.
concentration :
100ug/100ul
storage stability :
Store at 4 degree C, for long term storage, store at -20 degree C.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1/500 - 1/2000, IHC:1/200-1/1000, IF: 1/200-1/1000, . ELISA: Propose dilution 1/10000. Not yet tested in other applications.
other info2 :
Immunogen: Purified recombinant fragment of human CARM1 expressed in E. Coli. Species: Mouse IgG1
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.
ncbi acc num :
NP_001121689.1
ncbi gb acc num :
NM_001128217.1
ncbi pathways :
2-LTR Circle Formation Pathway 105993!!APOBEC3G Mediated Resistance To HIV-1 Infection Pathway 106016!!Autointegration Results In Viral DNA Circles Pathway 105994!!Disease Pathway 530764!!Early Phase Of HIV Life Cycle Pathway 105985!!HIV Infection Pathway 105983!!HIV Life Cycle Pathway 105984!!Host Interactions Of HIV Factors Pathway 106010!!Integration Of Provirus Pathway 105991!!Integration Of Viral DNA Into Host Genomic DNA Pathway 205240