product summary
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company name :
MyBioSource
product type :
antibody
product name :
GRK2 Antibody
catalog :
MBS850581
quantity :
0.1 mg
price :
290 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3F8
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS850581
products type :
Antibody
products full name :
GRK2 Antibody
products short name :
GRK2
products name syn :
GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1
other names :
beta-adrenergic receptor kinase 1; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1; beta-ARK-1; G-protein coupled receptor kinase 2; adrenergic, beta, receptor kinase 1; G-protein coupled receptor kinase 2
products gene name :
GRK2
other gene names :
ADRBK1; ADRBK1; GRK2; BARK1; BETA-ARK1; BARK; BARK1; GRK2; Beta-ARK-1
uniprot entry name :
ARBK1_HUMAN
clonality :
Monoclonal
clone :
3F8
host :
Mouse
reactivity :
Human, Mouse, Rat, Monkey
sequence length :
689
form :
Ascitic fluid containing 0.03% sodium azide.
concentration :
100ug/100ul
storage stability :
Store at 4 degree C, for long term storage, store at -20 degree C.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications.
other info2 :
Immunogen: Purified recombinant fragment of human GRK2 expressed in E. Coli. Species: Mouse IgG1
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes
ncbi gi num :
148539876
ncbi acc num :
NP_001610.2
ncbi gb acc num :
NM_001619.3
ncbi mol weight :
80kDa
ncbi pathways :
CXCR4-mediated Signaling Events Pathway 137910!!Ca-dependent Events Pathway 106497!!CaM Pathway 106468!!Calmodulin Induced Events Pathway 106469!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!DAG And IP3 Signaling Pathway 477115!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764
ncbi summary :
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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