catalog number :
MBS8505326
products full name :
NTS Antibody
products short name :
[NTS]
other names :
[neurotensin/neuromedin N preproprotein; Neurotensin/neuromedin N; neurotensin/neuromedin N; neurotensin; Large neuromedin NAlternative name(s):NmN-125]
products gene name :
[NTS]
other gene names :
[NTS; NTS; NN; NT; NT/N; NTS1; NMN-125; NN; NmN; NT]
ncbi acc num :
NP_006174.1
ncbi gb acc num :
NM_006183.4
ncbi mol weight :
19,795 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014]
uniprot summary :
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.