antibody

LMP1 Antibody

MBS8504781

0.1 mL

310 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry

Antibody

LMP1 Antibody

[LMP1]

[PDLIM7; LMP1; LMP3]

[PDZ and LIM domain protein 7 isoform 1; PDZ and LIM domain protein 7; PDZ and LIM domain protein 7; PDZ and LIM domain 7; LIM mineralization protein; LMP; Protein enigma]

[LMP1]

[PDLIM7; PDLIM7; LMP1; LMP3; ENIGMA; LMP]

polyclonal

IgG

rabbit

Human, Mouse, Rat

457

Affinity purification

Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.

Western Blot (WB), Immunohistochemistry (IHC)

WB: 1:500-1:1000. IHC: 1:50-1:100

Western Blot (WB)

Immunogen: Fusion protein of human LMP1. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

11496885

NP_005442.2

NM_005451.4

Q9NR12

55kDa

Signaling Events Regulated By Ret Tyrosine Kinase Pathway (137915)

The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway ().

0.1 mL

310 USD