product summary
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company name :
MyBioSource
product type :
antibody
product name :
Foxp3 Antibody
catalog :
MBS850429
quantity :
0.1 mg
price :
290 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2A11G9
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS850429
products type :
Antibody
products full name :
Foxp3 Antibody
products short name :
Foxp3
products name syn :
JM2; AIID; IPEX; PIDX; XPID; DIETER; Foxp3
other names :
forkhead box protein P3 isoform b; Forkhead box protein P3; forkhead box protein P3; scurfin; FOXP3delta7; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; forkhead box P3; Scurfin
products gene name :
Foxp3
other gene names :
FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; IPEX
uniprot entry name :
FOXP3_HUMAN
clonality :
Monoclonal
clone :
2A11G9; 2A11C2
host :
Mouse
reactivity :
Human, Mouse
sequence length :
396
form :
Purified antibody in PBS containing 0.03% sodium azide.
concentration :
100ug/100ul
storage stability :
Store at 4 degree C, for long term storage, store at -20 degree C
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA(EIA)
app notes :
WB: 1/500 - 1/2000, IHC:1/200 - 1/1000, IF: 1/200 - 1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
other info2 :
Immunogen: Purified recombinant fragment of human Foxp3 expressed in E. Coli. Species: Mouse IgG1
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: The transcription factor Foxp family includes Foxp1, Foxp2, and Foxp3. The Foxp3 (50KDa)plays a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4(+) CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
ncbi gi num :
167466190
ncbi acc num :
NP_001107849.1
ncbi gb acc num :
NM_001114377.1
ncbi mol weight :
44,407 Da
ncbi pathways :
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!IL2 Signaling Events Mediated By STAT5 Pathway 137988!!Inflammatory Bowel Disease (IBD) Pathway 842771!!Inflammatory Bowel Disease (IBD) Pathway 842797
ncbi summary :
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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