product summary
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company name :
MyBioSource
product type :
antibody
product name :
EPOR Antibody
catalog :
MBS8503871
quantity :
0.1 mL
price :
310 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using EPOR antibody.
product information
catalog number :
MBS8503871
products type :
Antibody
products full name :
EPOR Antibody
products short name :
[EPOR]
products name syn :
[EPO-R]
other names :
[erythropoietin receptor; Erythropoietin receptor; erythropoietin receptor; erythropoietin receptor]
products gene name :
[EPOR]
other gene names :
[EPOR; EPOR; EPO-R; EPO-R]
clonality :
polyclonal
isotype :
IgG
host :
rabbit
reactivity :
Human, Mouse, Rat
sequence length :
508
purity :
Affinity purification
storage stability :
Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide of human EPOR. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products description :
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
ncbi gi num :
4503591
ncbi acc num :
NP_000112.1
ncbi gb acc num :
NM_000121.3
uniprot acc num :
P19235
ncbi mol weight :
55kDa
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); EPO Receptor Signaling Pathway (198882); EPO Signaling Pathway (138051); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Kit Receptor Signaling Pathway (198826); PI3K-Akt Signaling Pathway (692234)
ncbi summary :
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
uniprot summary :
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
size1 :
0.1 mL
price1 :
310 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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