antibody

WNT5A Antibody

MBS850386

0.1 mg

290 USD

monoclonal

mouse

nonconjugated

3D10

western blot, ELISA, immunohistochemistry, enzyme immunoassay

Antibody

WNT5A Antibody

WNT5A

hWNT5A;

protein Wnt-5a isoform 2; Protein Wnt-5a; protein Wnt-5a; WNT-5A protein; wingless-type MMTV integration site family, member 5A

WNT5A

WNT5A; WNT5A; hWNT5A

WNT5A_HUMAN

Monoclonal

3D10

Mouse

Human

365

Ascitic fluid containing 0.03% sodium azide.

100ug/100ul

Store at 4 degree C. For long term storage, store at -20 degree C

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.

Immunogen: Purified recombinant fragment of WNT5A expressed in E. Coli. Species: Mouse IgG1

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Background: WNT5A. wingless-type MMTV integration site family, member 5A. Entrez Protein. NP_003383. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.

371502087

NP_001243034.1

NM_001256105.1

42.3kDa

Asymmetric Localization Of PCP Proteins Pathway 941396!!Basal Cell Carcinoma Pathway 83113!!Basal Cell Carcinoma Pathway 525!!Ca2+ Pathway 941399!!Class B/2 (Secretin Family Receptors) Pathway 106378!!DNA Damage Response (only ATM Dependent) Pathway 198827!!Disease Pathway 530764!!GPCR Ligand Binding Pathway 161020!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

0.1 mg

290 USD