antibody

BNP Antibody

MBS850376

0.1 mg

290 USD

monoclonal

mouse

nonconjugated

9H6B4

ELISA, immunohistochemistry, enzyme immunoassay

Antibody

BNP Antibody

BNP

BNP; NPPB

natriuretic peptides B preproprotein; Natriuretic peptides B; natriuretic peptides B; natriuretic protein; brain type natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor B; natriuretic peptide B; Gamma-brain natriuretic peptideCleaved into the following 16 chains:Brain natriuretic peptide 32; BNP(1-32); BNP-32; BNP(1-30); BNP(1-29); BNP(1-28); BNP(2-31); BNP(3-32); BNP(3-30); BNP(3-29); BNP(4-32); BNP(4-31); BNP(4-30); BNP(4-29); BNP(4-27); BNP(5-32); BNP(5-31); BNP(5-29)

BNP

NPPB; NPPB; BNP; BNP(1-32); BNP-32

ANFB_HUMAN

Monoclonal

9H6B4; 9H6H4A7

Mouse

Human

134

Ascitic fluid containing 0.03% sodium azide.

100ug/100ul

Store at 4 degree C. For long term storage, store at -20 degree C

Immunohistochemistry (IHC), ELISA (EIA)

IHC:1/200 - 1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.

Immunogen: Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH. Species: Mouse IgG1

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Background: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

4505433

NP_002512.1

NM_002521.2

14,726 Da

MicroRNAs In Cardiomyocyte Hypertrophy Pathway 198784!!CGMP-PKG Signaling Pathway 983748!!CGMP-PKG Signaling Pathway 985584

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

0.1 mg

290 USD