IGF2 Antibody | MyBioSource MBS8502949 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

IGF2 Antibody

catalog :

MBS8502949

quantity :

0.1 mL

price :

310 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of extracts of various celllines, using IGF2 antibody.

product information

catalog number :

MBS8502949

products type :

Antibody

products full name :

IGF2 Antibody

products short name :

[IGF2]

products name syn :

[IGF-II; PP9974; C11orf43]

other names :

[insulin-like growth factor II isoform 1 preproprotein; Insulin-like growth factor II; insulin-like growth factor II; insulin like growth factor 2; Somatomedin-A; T3M-11-derived growth factor]

products gene name :

[IGF2]

other gene names :

[IGF2; IGF2; GRDF; IGF-II; PP9974; C11orf43; IGF-II]

clonality :

polyclonal

isotype :

IgG

host :

rabbit

reactivity :

Human, Mouse, Rat

sequence length :

180

purity :

Affinity purification

storage stability :

Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB: 1:500-1:2000. IHC: 1:50-1:200

image1 heading :

Testing Data

other info1 :

Immunogen: Recombinant protein of human IGF2. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

products categories :

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

products description :

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilmstumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

ncbi gi num :

4504609

ncbi acc num :

NP_000603.1

ncbi gb acc num :

NM_000612.5

uniprot acc num :

P01344

ncbi mol weight :

20kDa

ncbi pathways :

Apoptosis Pathway (198797); Cardiac Progenitor Differentiation Pathway (712094); Endochondral Ossification Pathway (198812); Hedgehog Signaling Pathway (198835); Hemostasis Pathway (106028); IGF1R Signaling Cascade Pathway (730346); IRS-related Events Triggered By IGF1R Pathway (730348); Metabolism Of Proteins Pathway (106230); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050)

ncbi summary :

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

uniprot summary :

The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable).

size1 :

0.1 mL

price1 :

310 USD

more info or order :

MyBioSource product webpage

company information

MyBioSource

P.O. Box 153308
San Diego, CA 92195-3308

sales@mybiosource.com

https://www.mybiosource.com

1-888-627-0165

headquarters: USA

MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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