product summary
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company name :
MyBioSource
product type :
antibody
product name :
ISL1 Antibody
catalog :
MBS850276
quantity :
0.1 mg
price :
290 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1H9
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS850276
products type :
Antibody
products full name :
ISL1 Antibody
products short name :
ISL1
products name syn :
Isl-1; ISLET1
other names :
insulin gene enhancer protein ISL-1; Insulin gene enhancer protein ISL-1; insulin gene enhancer protein ISL-1; islet-1; ISL1 transcription factor, LIM/homeodomain; ISL LIM homeobox 1
products gene name :
ISL1
other gene names :
ISL1; ISL1; Isl-1; ISLET1; Islet-1
uniprot entry name :
ISL1_HUMAN
clonality :
Monoclonal
clone :
1H9
host :
Mouse
reactivity :
Human
sequence length :
349
form :
Ascitic fluid containing 0.03% sodium azide.
concentration :
100ug/100ul
storage stability :
Store at 4 degree C. For long term storage, store at -20 degree C
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
other info2 :
Immunogen: Purified recombinant fragment of human ISL1 expressed in E. Coli. Species: Mouse IgG1
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
ncbi gi num :
115387114
ncbi acc num :
NP_002193.2
ncbi gb acc num :
NM_002202.2
ncbi mol weight :
39kDa
ncbi pathways :
Cardiac Progenitor Differentiation Pathway 712094!!Heart Development Pathway 198802!!Incretin Synthesis, Secretion, And Inactivation Pathway 187170!!Metabolism Of Proteins Pathway 106230!!Neural Crest Differentiation Pathway 672460!!Peptide Hormone Metabolism Pathway 771603!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1026136!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1033502!!Synthesis, Secretion, And Inactivation Of Glucose-dependent Insulinotropic Polypeptide (GIP) Pathway 187172
ncbi summary :
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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