product summary
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company name :
MyBioSource
product type :
antibody
product name :
CIRBP Polyclonal Antibody
catalog :
MBS8502665
quantity :
0.1 mg
price :
310 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS8502665
products type :
Antibody
products full name :
CIRBP Polyclonal Antibody
products short name :
[CIRBP]
products name syn :
[CIRP]
other names :
[cold-inducible RNA-binding protein isoform 1; Cold-inducible RNA-binding protein; cold-inducible RNA-binding protein; cold inducible RNA binding protein; A18 hnRNP; Glycine-rich RNA-binding protein CIRP]
products gene name :
[CIRBP]
other gene names :
[CIRBP; CIRBP; CIRP; A18HNRNP; CIRP]
clonality :
polyclonal
host :
unknown
reactivity :
Human, Mouse, Rat
sequence length :
172
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
app notes :
WB: 1:200-1:2000. IHC: 1:50-1:200. IF: 1:50-1:100. IP: 1:20-1:50
other info1 :
Immunogen: Recombinant protein of human CIRBP
products description :
CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. CIRBP can translocate from nucleus to cytoplasm under stresses such as UV irradation or heat shock. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature. This antibody is a rabbit polyclonal antibody raised against the full-length CIRBP of human origin.
ncbi gi num :
4502847
ncbi acc num :
NP_001271.1
ncbi gb acc num :
NM_001280.2
uniprot acc num :
Q14011
ncbi mol weight :
19 KD
uniprot summary :
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (). Promotes assembly of stress granules (SGs), when overexpressed.
size1 :
0.1 mg
price1 :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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