This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
alpha-Actin SMA Antibody
catalog :
MBS850249
quantity :
0.1 ml
price :
290 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
33-32
reactivity :
human, mouse, rat
application :
western blot
product information
catalog number :
MBS850249
products type :
Antibody
products full name :
alpha-Actin SMA Antibody
products short name :
alpha-Actin SMA
products name syn :
a-Actin SMA Antibody
other names :
actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1; actin, alpha cardiac muscle 1; alphac-actin; actin alpha cardiac; alpha-cardiac actin; actin, alpha, cardiac muscle 1; Alpha-cardiac actin
other gene names :
Actc1; Actc1; Actc-1; Actc
uniprot entry name :
ACTC_MOUSE
clonality :
Monoclonal
clone :
33-32
host :
Mouse
reactivity :
Human, Mouse, Rat
sequence length :
377
specificity :
This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near N-terminal residues of CK17.
form :
Mouse monoclonal IgG 1 in 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
storage stability :
Store at 4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:5000
other info2 :
Cellular Localization: Cytoplasm
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: Actins are highly conserved proteins expressed in all eucaryotic cells. Actin filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner, alpha and beta cytoplasmic actins are expressed in a wide variety of cells; whereas, expression of alpha skeletal, alpha cardiac, alpha vascular, and gamma enteric actins are more restricted to specialized muscle cell type. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Further more, expression of smooth muscle alpha actin is regulated by hormones, cell proliferation, and altered by pathological conditions including oncogenic transformation and atherosclerosis.
products references :
1. The MGC Project Team. Genome Res. 14:2121-2127(2004). 2. Leader D.P., Gall I., Campbell P.C. Biosci. Rep. 6:741-747(1986). 3. Carninci P., Kasukawa T., Katayama S.etc. Science 309:1559-1563(2005).
ncbi gi num :
14192922
ncbi acc num :
NP_033738.1
ncbi gb acc num :
NM_009608.3
uniprot acc num :
P68033
ncbi mol weight :
42kDa
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway 908268!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Cardiac Muscle Contraction Pathway 93345!!Cardiac Muscle Contraction Pathway 93992!!Dilated Cardiomyopathy Pathway 121495!!Dilated Cardiomyopathy Pathway 121285!!Hypertrophic Cardiomyopathy (HCM) Pathway 114298!!Hypertrophic Cardiomyopathy (HCM) Pathway 106591!!Myometrial Relaxation And Contraction Pathways 198333!!Striated Muscle Contraction Pathway 198348
size :
0.1 ml
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!