product summary
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company name :
MyBioSource
product type :
antibody
product name :
PRCP Antibody
catalog :
MBS8502445
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS8502445
products type :
Antibody
products full name :
PRCP Antibody
products short name :
[PRCP]
other names :
[lysosomal Pro-X carboxypeptidase isoform 1 preproprotein; Lysosomal Pro-X carboxypeptidase; lysosomal Pro-X carboxypeptidase; prolylcarboxypeptidase; Angiotensinase C; Lysosomal carboxypeptidase C; Proline carboxypeptidase; Prolylcarboxypeptidase; PRCP]
products gene name :
[PRCP]
other gene names :
[PRCP; PRCP; PCP; HUMPCP; PCP; PRCP]
clonality :
polyclonal
host :
rabbit
reactivity :
Human, Mouse
sequence length :
496
specificity :
PCP Polyclonal Antibody detects endogenous levels of protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS, containing 50% glycerol, and 0.02% sodium azide.
concentration :
1mg/ml, 100 ul
storage stability :
Store at -20°C/ 1 year.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500-2000. ELISA: 1:5000-20000
other info1 :
Signal Pathway: 54. Observed Band (KDa): 54
ncbi gi num :
4826940
ncbi acc num :
NP_005031.1
ncbi gb acc num :
NM_005040.3
uniprot acc num :
P42785
ncbi pathways :
Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028); Intrinsic Pathway (106059); Protein Digestion And Absorption Pathway (172847); Protein Digestion And Absorption Pathway (171868)
ncbi summary :
This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
uniprot summary :
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
size1 :
0.1 mg
price1 :
300 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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