product summary
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company name :
MyBioSource
product type :
other
product name :
E-cadherin Antibody
catalog :
MBS8502323
quantity :
0.1 mg
price :
300 USD
more info or order :
image
image 1 :
MyBioSource MBS8502323 image 1
Peptide: (Left image: -), (Right Image: +). Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissu using E-cadherin-pan antibody.
image 2 :
MyBioSource MBS8502323 image 2
Western Blot analysis of extracts from NIH/3T3 cells, using E-cadherin-pan antibody
product information
catalog number :
MBS8502323
products type :
Antibody
products full name :
E-cadherin Antibody
products short name :
[E-cadherin]
other names :
[cadherin-1 preproprotein; Cadherin-1; cadherin-1; cadherin 1; ARC-1; Epithelial cadherin; E-cadherin]
other gene names :
[Cdh1; Cdh1; Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649; E-cadherin]
sequence length :
884
image1 heading :
Immunohistochemistry
image2 heading :
Western Blot
ncbi gi num :
6753374
ncbi acc num :
NP_033994.1
ncbi gb acc num :
NM_009864.3
uniprot acc num :
P09803
ncbi mol weight :
98,256 Da
ncbi pathways :
Adherens Junction Pathway (83267); Adherens Junction Pathway (481); Adherens Junctions Interactions Pathway (1323791); Apoptosis Pathway (1323524); Apoptotic Cleavage Of Cell Adhesion Proteins Pathway (1323551); Apoptotic Cleavage Of Cellular Proteins Pathway (1323549); Apoptotic Execution Phase Pathway (1323548); Bacterial Invasion Of Epithelial Cells Pathway (149817); Bacterial Invasion Of Epithelial Cells Pathway (148661); Bladder Cancer Pathway (83308)
ncbi summary :
This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8. [provided by RefSeq, Oct 2015]
uniprot summary :
Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 ().
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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