catalog number :
MBS850197
products full name :
Antibody to IGFBP2 Antibody
products short name :
IGFBP2
products name syn :
IBP2; IGF-BP53
other names :
insulin-like growth factor-binding protein 2; Insulin-like growth factor-binding protein 2; insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2; insulin-like growth factor binding protein 2, 36kDa
products gene name :
IGFBP2
other gene names :
IGFBP2; IGFBP2; IBP2; IGF-BP53; BP2; IBP2; IBP-2; IGF-binding protein 2; IGFBP-2
uniprot entry name :
IBP2_HUMAN
form :
Ascitic fluid containing 0.03% sodium azide.
concentration :
100ug/100ul
storage stability :
Store at 4 degree C. For long term storage, store at -20 degree C
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
other info2 :
Immunogen: Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli. Species: Mouse IgG1
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: IGFBP2. insulin-like growth factor binding protein 2. IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
ncbi acc num :
NP_000588.2
ncbi gb acc num :
NM_000597.2
ncbi mol weight :
34,814 Da
ncbi pathways :
Metabolism Of Proteins Pathway 106230!!Myometrial Relaxation And Contraction Pathways 198759!!Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway 105908