product summary
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company name :
MyBioSource
product type :
other
product name :
MLKL Antibody
catalog :
MBS8501743
quantity :
0.1 mg
price :
300 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8501743 image 1
Western blot analysis of extracts of THP-1 celiline, using MLKL antibody
product information
catalog number :
MBS8501743
products type :
Antibody
products full name :
MLKL Antibody
products short name :
[MLKL]
other names :
[mixed lineage kinase domain-like protein isoform 2; Mixed lineage kinase domain-like protein; mixed lineage kinase domain-like protein; mixed lineage kinase domain-like]
products gene name :
[MLKL]
other gene names :
[Mlkl; Mlkl; 9130019I15Rik]
sequence length :
464
image1 heading :
Western blot
ncbi gi num :
110626037
ncbi acc num :
NP_083281.1
ncbi gb acc num :
NM_029005.3
uniprot acc num :
Q9D2Y4
ncbi mol weight :
53,375 Da
ncbi summary :
This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
uniprot summary :
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
size1 :
0.1 mg
price1 :
300 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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