catalog number :
MBS8501617
products full name :
XYLT1 Antibody
products short name :
[XYLT1]
other names :
[xylosyltransferase 1; Xylosyltransferase 1; xylosyltransferase 1; xylosyltransferase 1; Peptide O-xylosyltransferase 1; Xylosyltransferase I; XT-I; XylT-I]
products gene name :
[XYLT1]
other gene names :
[XYLT1; XYLT1; XT1; XTI; XT-I; DBQD2; XYLTI; PXYLT1; xylT-I; XT1; XT-I; XylT-I]
image1 heading :
Testing Data
image2 heading :
Testing Data #2
ncbi acc num :
NP_071449.1
ncbi gb acc num :
NM_022166.3
ncbi mol weight :
107,569 Da
ncbi pathways :
Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (82982); Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (356); Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway (82984); Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway (358); Glycosaminoglycan Biosynthesis, Linkage Tetrasaccharide Pathway (413363); Glycosaminoglycan Biosynthesis, Linkage Tetrasaccharide Pathway (468250); Metabolic Pathways (132956); Spinal Cord Injury Pathway (739007); Chondroitin Sulfate Biosynthesis Pathway (545279); Chondroitin Sulfate Biosynthesis Pathway (545411)
ncbi summary :
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]
uniprot summary :
Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.