IL-3R beta (Phospho-Tyr593) Antibody | MyBioSource MBS8501412 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

IL-3R beta (Phospho-Tyr593) Antibody

catalog :

MBS8501412

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS8501412

products type :

Antibody

products full name :

IL-3R beta (Phospho-Tyr593) Antibody

products short name :

IL-3R beta

products name syn :

IL-3Rb (Phospho-Tyr593) Antibody

other names :

cytokine receptor common subunit beta; Cytokine receptor common subunit beta; cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131

other gene names :

CSF2RB; CSF2RB; CD131; IL3RB; IL5RB; SMDP5; CDw131; IL3RB; IL5RB

uniprot entry name :

IL3RB_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse

sequence length :

897

specificity :

IL3R (Phospho-Tyr593) antibody detects endogenous levels of IL3R only when phosphorylated at tyrosine 593.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

concentration :

100ug/100ul

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

app notes :

WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:1000

other info1 :

All Names: Interleukin-3 receptor alpha chain, IL-3R-alpha, CD123 antigen, IL3RA. Swiss-Prot No. : P26951

other info2 :

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human IL3R around the phosphorylation site of tyrosine 593 (G-P-YP-L-G). All Sites: Human: Tyr593; Mouse: Tyr595

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Michelle M. Le Beau, Blood, Aug 2003; 102: 1072 - 1074. Elena Cattaneo, J. Biol. Chem., Sep 1996; 271: 23374. Patricia McLoughlin, J. Biol. Chem., Sep 2002; 277: 37045 - 37053. Louise Edvardsson, Blood, Nov 2004; 104: 4120.

ncbi gi num :

4559408

ncbi acc num :

NP_000386.1

ncbi gb acc num :

NM_000395.2

uniprot acc num :

P32927

ncbi mol weight :

97,976 Da

ncbi pathways :

Apoptosis Pathway (83060); Apoptosis Pathway (470); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL-3 Signaling Pathway (198881); IL-5 Signaling Pathway (198770); Immune System Pathway (106386); Interleukin Receptor SHC Signaling Pathway (187095); Interleukin-2 Signaling Pathway (205110)

ncbi summary :

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]

uniprot summary :

CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; interleukin-5 receptor activity; interleukin-3 receptor activity; receptor activity. Biological Process: response to lipopolysaccharide; respiratory gaseous exchange; signal transduction. Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage