catalog number :
MBS850115
products full name :
ACTA2 Antibody
products short name :
ACTA2
products name syn :
AAT6; ACTSA; ACTA2
other names :
actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; alpha-cardiac actin; cell growth-inhibiting gene 46 protein; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein
products gene name :
ACTA2
other gene names :
ACTA2; ACTA2; AAT6; ACTSA; MYMY5; ACTSA; ACTVS
uniprot entry name :
ACTA_HUMAN
reactivity :
Human, Monkey
form :
Ascitic fluid containing 0.03% sodium azide.
concentration :
100ug/100ul
storage stability :
Store at 4 degree C, for long term storage, store at -20 degree C.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), ELISA (EIA)
app notes :
WB: 1/500 - 1/2000, IHC: 1/200-1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications.
other info2 :
Immunogen: Purified recombinant fragment of human ACTA2 expressed in E. Coli. Species: Mouse IgG1
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: Actin, alpha 2, smooth muscle, aorta, major constituent of thin filaments.
ncbi acc num :
NP_001135417.1
ncbi gb acc num :
NM_001141945.1
ncbi pathways :
Muscle Contraction Pathway 106261!!Myometrial Relaxation And Contraction Pathways 198759!!Smooth Muscle Contraction Pathway 161025!!Striated Muscle Contraction Pathway 198903!!Vascular Smooth Muscle Contraction Pathway 96530!!Vascular Smooth Muscle Contraction Pathway 96866
ncbi summary :
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]