catalog number :
MBS8500767
products full name :
SDC2 Antibody
products short name :
[SDC2]
products name syn :
[HSPG; CD362; HSPG1; SYND2]
other names :
[syndecan-2; Syndecan-2; syndecan-2; syndecan 2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD_antigen: CD362]
products gene name :
[SDC2]
other gene names :
[SDC2; SDC2; HSPG; CD362; HSPG1; SYND2; HSPG1; SYND2; HSPG]
reactivity :
Human, Mouse, Rat
purity :
Affinity purification
storage stability :
Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000. IHC: 1:50-1:200
image1 heading :
Testing Data
other info1 :
Immunogen: Recombinant protein of human SDC2. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products description :
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]
ncbi acc num :
NP_002989.2
ncbi gb acc num :
NM_002998.3
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Axon Guidance Pathway (105688); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Defective B3GAT3 Causes JDSSDHD Pathway (1127588); Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway (1127592); Defective B4GALT7 Causes EDS, Progeroid Type Pathway (1127587); Defective CHST14 Causes EDS, Musculocontractural Type Pathway (1127591); Defective CHST3 Causes SEDCJD Pathway (1127590)
ncbi summary :
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]
uniprot summary :
Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis ().