antibody

ESR1 Antibody

MBS850005

0.1 mg

290 USD

monoclonal

mouse

nonconjugated

6B6

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

ESR1 Antibody

ESR1

ER; ESR; Era; ESRA; NR3A1; DKFZp686N23123; ESR1

estrogen receptor isoform 1; Estrogen receptor; estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; nuclear receptor subfamily 3 group A member 1; estrogen receptor 1; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1

ESR1

ESR1; ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1; ESR; NR3A1; ER

ESR1_HUMAN

Monoclonal

6B6

Mouse

Human

595

Ascitic fluid containing 0.03% sodium azide.

100ug/100ul

Store at 4 degree C, for long term storage, store at -20 degree C.

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000, ELISA: Propose dilution 1/10000. Not yet tested in other applications.

Immunogen: Purified recombinant fragment of human ESR1 expressed in E. Coli. Species: Mouse IgG1

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

62821794

NP_000116.2

NM_000125.3

66kDa

Endocrine And Other Factor-regulated Calcium Reabsorption Pathway 213307!!Endocrine And Other Factor-regulated Calcium Reabsorption Pathway 213276!!Estrogen Signaling Pathway 799177!!Estrogen Signaling Pathway 198863!!Estrogen Signaling Pathway 799197!!FOXA1 Transcription Factor Network Pathway 137979!!FOXM1 Transcription Factor Network Pathway 137935!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!Integrated Breast Cancer Pathway 219801

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

0.1 mg

290 USD