product summary
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company name :
MyBioSource
product type :
protein
product name :
TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant
catalog :
MBS845223
quantity :
0.02 mg
price :
245 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS845223 image 1
product information
catalog number :
MBS845223
products type :
Recombinant Protein
products full name :
TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant
products short name :
[TDRD12-BD2]
products name syn :
[ECAT8]
other names :
[putative ATP-dependent RNA helicase TDRD12; Putative ATP-dependent RNA helicase TDRD12; putative ATP-dependent RNA helicase TDRD12; tudor domain containing 12; ES cell-associated transcript 8 protein; Tudor domain-containing protein 12]
products gene name :
[TDRD12]
other gene names :
[TDRD12; TDRD12; ECAT8; ECAT8]
uniprot entry name :
TDR12_HUMAN
host :
E Coli
sequence positions :
[908-999]
sequence length :
395
purity :
>=98% by SDS-PAGE.
form :
Liquid. rh-TDRD12-BD2 is supplied as a solution (2mg/mL) in PBS Buffer containing 10% glycerol
storage stability :
Stable for 1 year at -80°C. Avoid multiple freeze/thaw cycles as activity may decrease. Ships with dry ice.
image1 heading :
Testing Data
other info2 :
Application and USAGE: TDRD12 is useful in studying bromodomain binding assays,screening inibitors and selectivity profiling.
products categories :
Epigenetics; Reader Domains; Tudor Domains; Tudor Domain ProteinsProteins and Enzymes; Animal-Free Origin (AOF) Recombinant Proteins & EnzymesProteins and Enzymes; Proteins and Enzymes (A-Z)
products description :
Background: Tudor domains are small protein structural motifs of about ~50 amino acids related to the "royal family" of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.
ncbi gi num :
161016765
ncbi acc num :
NP_001104292.1
ncbi gb acc num :
NM_001110822.1
uniprot acc num :
Q587J7
ncbi mol weight :
13 kDa (91 aa, 908-999 aa+ NT 6X His Tag)
ncbi pathways :
Gene Expression Pathway (1269649); PIWI-interacting RNA (piRNA) Biogenesis Pathway (1269724); Regulatory RNA Pathways (1269719)
uniprot summary :
TDRD12: 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.6.4.13. Chromosomal Location of Human Ortholog: 19q13.11. Molecular Function: nucleic acid binding; helicase activity; ATP binding. Biological Process: fertilization; multicellular organismal development; DNA methylation during gametogenesis; spermatogenesis; RNA-mediated gene silencing; gene expression; male meiosis; cell differentiation
size1 :
0.02 mg
price1 :
245 USD
size2 :
0.1 mg
price2 :
655
size3 :
1 mg
price3 :
5015
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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