product summary
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company name :
MyBioSource
product type :
antibody
product name :
Nitrotyrosine Antibody
catalog :
MBS841318
quantity :
0.05 mL
price :
305 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS841318
products type :
Antibody
products full name :
Nitrotyrosine Antibody
products short name :
[Nitrotyrosine]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
All species
specificity :
Does not react with nitrotyrosine-unmodified cell extract or purified proteins.
form :
Supplied as rabbit serum. Does not contain sodium azide. Appearance: Provided as rabbit serum
storage stability :
After initial thaw, aliquot into individual tubes and refreezes at -20 degree C to -70 degree C. Avoid repeated freeze/tahw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
Western blotting 1/500 using alkaline phosphatase and BCIP/NBT, ELISA (Recognizes nitrated BSA 1/1,000,000 in ELISA).
other info1 :
Immunogen: Nitrated keyhole limpet hemocyanin (KLH).
other info2 :
Handling: The antibody solution should be gently mixed before use.
products categories :
Antibodies & Supporting ToolsApoptosis & Related Products; Apoptosis AntibodiesCell Damage & Oxidative Stress; Cell Damage & Oxidative Stress Antibodies (Make new category)
products description :
Background: Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species such as peroxynitrite anion and nitrogen dioxide. It is a marker for inflammation and nitric oxide (NO) production. It is detected in large number of pathological conditions and is considered a marker of NO-dependent, reactive nitrogen species-induced nitrative stress. Tyrosine nitration can inactivate enzymes and receptors that depend on tyrosine residues for their activity. Nitration prevents phosphorylation of tyrosine residues important for signal transduction. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques, chronic renal failure and keratoconus. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine Antibody detects proteins and peptides containing nitro-tyrosine in a manner independent of the surrounding amino acid sequence. It is a valuable tool for identifying new nitrated proteins as well as for assaying protein nitration and measuring levels of nitrated proteins in tissues and samples.
size1 :
0.05 mL
price1 :
305 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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