catalog number :
MBS841261
products full name :
SPHKAP Antibody
products short name :
[SPHKAP]
products name syn :
[A-kinase anchor protein SPHKAP; SPHK1 interactor; AKAP domain containing; DKFZp781H143; DKFZp781J171; KIAA1678; MGC132614 antibody; MGC132616; SKIP antibody; A-kinase anchor protein Sphingosine kinase type 1-interacting protein; SPHK1 (Sphingosine kinase type 1) interacting protein; SPHK1-interactor and AKAP domain-containing protein; SPHK1 interactor; AKAP domain.]
other names :
[A-kinase anchor protein SPHKAP isoform 1; A-kinase anchor protein SPHKAP; A-kinase anchor protein SPHKAP; SPHK1 interactor, AKAP domain containing; SPHK1-interactor and AKAP domain-containing protein; Sphingosine kinase type 1-interacting protein]
products gene name :
[SPHKAP]
other gene names :
[SPHKAP; SPHKAP; SKIP; KIAA1678; SKIP]
uniprot entry name :
SPKAP_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Detects a ~181kDa band in Western Blot. Other applications have not been determined.
purity :
Affinity Purified Antibody
form :
100 ug (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
concentration :
0.5 mg/ml
storage stability :
At -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
Western blot: 1-4 ug/ml.
other info1 :
Immunogen: Synthetic peptide at C-terminal (BV-L21) . Positive Control: Western blot: Jurkat Cell lysate
other info2 :
Handling: The antibody solution should be gently mixed before use. Appearance: liquid
products categories :
Antibodies & Supporting Tools; Primary Antibodies (A-Z)Signaling Pathways; MAP Kinase Pathway; Antibodies
products description :
Polyclonal Antibody to detect SPHKAP in human, mouse and rat samples. Background: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.
ncbi acc num :
NP_001136116.1
ncbi gb acc num :
NM_001142644.1
ncbi mol weight :
183,414 Da
uniprot summary :
SPHK1IP: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. Belongs to the AKAP110 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 2q36. Cellular Component: mitochondrion; Z disc. Molecular Function: protein binding; protein kinase A binding