catalog number :
MBS841010
products full name :
Resistin Antibody
products short name :
[Resistin]
products name syn :
[RETN; RETN1; ADSF; Adipocyte Secreted Factor; FIZZ3; FIZZ 3]
other names :
[resistin; Resistin; resistin; resistin; Adipose tissue-specific secretory factor; ADSF; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3]
other gene names :
[RETN; RETN; ADSF; RSTN; XCP1; FIZZ3; RETN1; FIZZ3; HXCP1; RSTN; ADSF]
uniprot entry name :
RETN_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity purified rabbit IgG
form :
Supplied in phosphate buffered saline (PBS), pH 7.2 containing 30% glycerol,0.5 BSA, and 0.01% thimerosal.
concentration :
0.5 mg/ml
storage stability :
Store at -20°C. For long term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
tested application :
Western Blot (WB)
app notes :
Western blot analysis (0.5-4 ug/ml). This information is only intended as a guide. The optimal dilutions must be determined by the user.
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant human Resistin
other info2 :
Handling: The antibody solution should be gently mixed before use.
products description :
Background: Resistin (also called adipose tissue-specific secretory factor, ADSF) is a member of the family of adipocyte secreted proteins. Resistin appears to act on skeletal muscle myocytes, hepatocytes, and adipocytes themselves, where it is smuggested to reduce insulin sensitivity leading to type 2 diabetes.
ncbi gb acc num :
NM_020415.3
ncbi pathways :
Adipogenesis Pathway (198832)
ncbi summary :
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
uniprot summary :
resistin: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Belongs to the resistin/FIZZ family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: extracellular space; nucleus. Molecular Function: hormone activity. Biological Process: fat cell differentiation; response to mechanical stimulus; positive regulation of smooth muscle cell proliferation; positive regulation of smooth muscle cell migration; positive regulation of synaptic transmission; aging; response to insulin stimulus. Disease: Diabetes Mellitus, Noninsulin-dependent