product summary
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company name :
MyBioSource
product type :
antibody
product name :
IL-15 Antibody
catalog :
MBS840403
quantity :
0.1 mg
price :
305 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot
more info or order :
image
image 1 :
product information
catalog number :
MBS840403
products type :
Antibody
products full name :
IL-15 Antibody
products short name :
[IL-15]
products name syn :
[IL-15; IL15; IL 15; Interluekin-15; Interluekin 15; interluekin]
other names :
[interleukin-15; Interleukin-15; interleukin-15; interleukin 15]
products gene name :
[IL-15]
other gene names :
[Il15; Il15; IL-15; AI503618; IL-15]
uniprot entry name :
IL15_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
sequence length :
162
form :
100 ug (0.5 mg/ml) Protein A purified rabbit anti-mouse IL-15 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
storage stability :
Store at -20°C . For long-term storage aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
tested application :
Western Blot (WB)
app notes :
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
image1 heading :
Testing Data
other info1 :
Immunogen: E. coli-expressed mouse IL-15
other info2 :
Handling: The antibody solution should be gently mixed before use.
products description :
Background: IL-15 is a member of the four alpha-helical bundle family of cytokines with a molecular weight of 14-15 kDa. Its in vitro activity is very similar to IL-2, except that IL-15 utilizes the IL-15 receptor alpha subunit for binding. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes. It also activates a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses, allograpt rejection, and the pathogenesis of autoimmune diseases.
ncbi gi num :
6680407
ncbi acc num :
NP_032383
ncbi gb acc num :
NM_008357.2
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response (BioCarta) Pathway (198283); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); Herpes Simplex Infection Pathway (377874); Herpes Simplex Infection Pathway (377865); Intestinal Immune Network For IgA Production Pathway (128761); Intestinal Immune Network For IgA Production Pathway (128670); Jak-STAT Signaling Pathway (83274)
uniprot summary :
IL15: Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. Belongs to the IL-15/IL-21 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine; Cell cycle regulation; Secreted, signal peptide; Secreted. Cellular Component: nucleoplasm; extracellular space; cell surface; cytoplasm; extracellular region. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine activity. Biological Process: positive regulation of interleukin-17 production; NK T cell proliferation; positive regulation of immune response; positive regulation of natural killer cell proliferation; negative regulation of smooth muscle cell proliferation; cell maturation; signal transduction; lymph node development; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of natural killer cell differentiation; extrathymic T cell selection; natural killer cell differentiation; positive regulation of cell proliferation; immune response; regulation of T cell differentiation; positive regulation of T cell proliferation; regulation of defense response to virus by host; hyaluronan metabolic process
size1 :
0.1 mg
price1 :
305 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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