catalog number :
MBS840330
products full name :
ROBO4 Antibody
products short name :
[ROBO4]
products name syn :
[UNQ421/PRO3674; ECSM4; FLJ20798; MGC133352; MGC133353; MRB]
other names :
[roundabout homolog 4; Roundabout homolog 4; roundabout homolog 4; roundabout guidance receptor 4]
products gene name :
[ROBO4]
other gene names :
[Robo4; Robo4]
uniprot entry name :
ROBO4_RAT
purity :
Affinity purified
form :
0.5mg/ml in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
storage stability :
Store at -20°C. For long term, store at -70°C. Avoid repeated freeze/thawcycles
tested application :
The antibody can be used in Western Blot (1-4 ?g/ml).However, the optimal concentrations should be determined individually. Blocking peptide (MBS843949) is available separately.
app notes :
Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects the ROBO4 band in human samples.
image1 heading :
Testing Data
other info1 :
Immunogen: Synthetic peptide surrounding amino acid 322 of rat ROBO4
other info2 :
Handling: The antibody solution should be gently mixed before use.
products categories :
Antibodies & Supporting Tools; Primary Antibodies (A-Z)
products description :
Background: ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type domains. ROBO4 is predominantly expressed in vascular endothelium and is considered important for vascular development. ROBO4 is a receptor for Slit proteins and may mediate the inhibition of primary endothelial cell migration by Slit proteins.
ncbi acc num :
NP_852040.1
ncbi gb acc num :
NM_181375.1
uniprot summary :
ROBO4: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Belongs to the immunoglobulin superfamily. ROBO family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Cellular Component: external side of plasma membrane. Molecular Function: receptor activity. Biological Process: angiogenesis; cell differentiation; negative regulation of cell migration