catalog number :
MBS840003
products full name :
Anti-PEG Antibody (Clone 09F02)
products short name :
[PEG]
products name syn :
[Polyethylene Glycol]
products gene name :
[PEG]
reactivity :
All. It reacts with PEGylated proteins such as PEG-GCSF, PEG-Erythropoietin, and PEG-Interferon, but does not react to unmodified form of the same proteins.
specificity :
Reacts with all PEGylated proteins.
purity :
Protein A chromatography from in vitro production
form :
1 mg/ml in 0.1 M Sodium Acetate/0.15 M NaCl, pH 5.0
storage stability :
Store at -20 to -80°C; avoid repeat freeze-thaw cycles
tested application :
ELISA, Serves as Positive Control for Drug Detection Assays.
image1 heading :
ELISA (EIA)
other info1 :
Immunogen: PEG-KLH. pI: > 7.8. Appearance: Colorless liquid
products categories :
Antibodies & Supporting Tools; Tag Antibodies
products description :
Polyethylene Glycol (PEG) is a polymer of ethylene oxide available in size variants from 400 Da to 40 kDa. It is nonionic, nontoxic, biocompatible, strong, hydrophilic and has a large exclusion volume in aqueous solution. PEG has a number of industrial and biomedical applications. The modification of a biopharmaceutical with PEG increases its hydrodynamic radius, reduces immunogenicity and proteolytic cleavage. In particular, therapeutic proteins are conjugated with PEG to slow down their clearance from circulation and improve bioavailability. PEG antibodies can be a vital tool for propelling therapeutics to market by serving as a positive control anti-drug antibody, measuring clearance of a drug, or simply as a QA release confirming PEGylation.